GRANULATION et AGGLOMERATION

Granulation and agglomeration are both processes used to combine smaller particles into larger ones, but they differ in methods, objectives, and applications. Here's a breakdown of the key differences: GRANULATION Granulation is a more specific and controlled process used to create granules of uniform size and density. Granulation focuses on creating granules with uniform size, shape, and mechanical strength for applications that demand consistency, such as tablet formulation in pharmaceuticals. Granulation is commonly used where precise dosing and controlled release are critical. Benefits of Granulation : Improved Flowability and Handling Enhanced Stability of Actives Precise Dosing and Uniformity Improved Sensory Properties Customizable Release Profiles Enhanced Bioavailability Better Compressibility for Tablets Improved Taste Masking Reduced Dust and Enhanced Safety Optimized Storage and Stability ________________________________________ AGGLOMERATION Agglomeration is a broader term encompassing various processes that join smaller particles into larger clusters or aggregates. It focuses on improving handling properties or functional characteristics of powders. Agglomeration is often used to reduce dust, improve flowability, enhance solubility, or make materials easier to handle and process. Agglomerated particles are typically more porous, less dense, and vary in size. Agglomeration is widely used where solubility, dispersibility, and consumer-friendly properties are key. Benefits of Agglomeration : Improved Texture and Application Enhanced Dispersion in Formulations Protection of Sensitive Actives Ease of Handling and Processing Enhanced Solubility and Dissolution Improved Bioavailability Customized Particle Properties Dust Reduction and Safety Improved Storage and Stability Sustainability and Efficiency Customizable Solutions